CA Penarol experienced a shocking 0-2 home defeat to Cerro Largo in the Uruguay Primera Division on March 31, 2025. The match at the Estadio Campeón del Siglo saw the visitors from Melo execute a perfect game plan to stun one of Uruguay's most storied clubs. Cerro Largo absorbed early pressure and scored against the run of play late in the first half, taking a crucial lead into the break. Penarol emerged with renewed vigor but were caught on the counter-attack midway through the second half, with Cerro Largo doubling their advantage. The home side threw men forward but found Cerro Largo's defense in imperious form, with their goalkeeper also making several key stops. The victory was historic for Cerro Largo, one of their most significant away wins, while for Penarol it was a deeply disappointing result that raised questions during their title challenge.