Palestino secured an important 2-1 away victory against Club Atlético Unión in their Copa Sudamericana group opener on May 8, 2025. The Chilean side showed great resilience to come from behind after Unión took an early lead from a penalty kick. Palestino grew into the game and equalized before halftime with a well-worked team move, and then snatched all three points with a late winner in the 85th minute, a powerful header from a corner. The match was fiercely contested, with both teams creating chances, but Palestino's clinical edge in the final moments proved decisive. The win gave Palestino a perfect start in the group, putting immediate pressure on their rivals, while it was a disappointing home defeat for Unión. The Unión manager expressed frustration at conceding from a set-piece so late, while the Palestino coach praised his team's fighting spirit and character on the road. The starting XIs featured Unión's physical Argentine league players and Palestino's dynamic South American mix.