The Detroit Pistons fell to the Cleveland Cavaliers 95-116 at home in an NBA regular season game on October 28, 2025. The Cavaliers dominated the second half to run away with a convincing 21-point victory, handing the Pistons a tough loss. Cleveland's star players took over after a close first half, orchestrating a decisive third-quarter run that broke the game open. The Pistons' offense became stagnant, and they were unable to contain the Cavaliers' balanced attack, which featured efficient scoring from both the perimeter and the paint. This result dropped Detroit's early-season record while solidifying Cleveland's position as a contender in the Eastern Conference. The Pistons' coach emphasized the need for better defensive communication following the lopsided defeat.